Data

UMAP

No integration needed.

Markers

resolution : 0.1
total 5 clusters

Marker gene dotplot

Cluster annotation
cluster0 : Antigen presenting cell + macrophage
cluster1 : Neutrophil
cluster2 : T cell
cluster3 : Macrophage
cluster4 : Antigen presenting cell

Cluster2 : clonotype-associated cluster

Marker genes longer version

Genes were selected by Sung.

Heatmap

DEGs between ADU/CTL

Significant genes cutoff
FDR=0.05
fold change=1.2

Cluster0

Cluster1

Cluster2

Cluster3

Cluster4



GSEA of DEGs

Cluster3 : Macrophage

Hallmark pathway enrichment

Cluster0

Cluster1

Cluster2

Comparison of Interferon genes

Interferon-related genes

Isg15, Isg20, Ifitm3, Ifit1, Ifit3, Ifngr1, Irf7, Irf5, Irf8, Irf3

Cluster 3

Cluster 0

Cluster 1

Cluster 2

Volcanoplot

Cluster 3

Cluster 0

Cluster 1

Cluster 2